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UPEC Transcriptomes from infected urine samples
Transcriptomes from UPEC infected urine samples collected in the Emergency Room and Urology ward at the Universitätsspital Basel. -
UPEC + E. coli wildtype microscopy images
190 UPEC and E. coli wildtype strains grown in LB, MHB, and SHU to stationary, late-expoential, mid-exponential, and early-exponential phase. Single time point imaging, using... -
Proteomics of CFT073 in LB vs SHU2.5 with many replicates
Experiment performed as a reference experiment 32 samples: 2 conditions: LB, SHU2.5 by Benjamin Sellner + iron vs LB (both early exponential) 4 biological replicates of each... -
Characterization of a transwell-based microfluidic platform for...
This dataset contains original data collected during our study on the development and characterization of a transwell-based microfluidic platform designed for high-resolution... -
High-Resolution Imaging of Airway Tissues in a Transwell-Based Microfluidic Platform
This dataset comprises original imaging data obtained throughout our study on the development and characterization of a transwell-based microfluidic platform for high-resolution... -
Crystal structure of E. coli BAM in complex with darobactin
Antibiotics that target Gram-negative bacteria in new ways are needed to resolve the antimicrobial resistance crisis. Gram-negative bacteria are protected by an additional outer... -
Dynamic persistence of intracellular bacterial communities of uropathogenic...
Uropathogenic Escherichia coli (UPEC) proliferate within superficial bladder umbrella cells to form intracellular bacterial communities (IBCs) during early stages of urinary... -
Early invasion of the bladder wall by solitary bacteria protects...
Recurrence of uropathogenic Escherichia coli (UPEC) infections has been attributed to reactivation of quiescent intracellular reservoirs (QIRs) in deep layers of the bladder... -
Crystal structure of E. coli BAM in complex with dynobactin A
Discovery of antibiotics acting against Gram-negative species is uniquely challenging due to their restrictive penetration barrier. BamA, which inserts proteins into the outer... -
Antibiotic persistence of intracellular Brucella abortus
Background Human brucellosis caused by the facultative intracellular pathogen Brucella spp. is an endemic bacterial zoonosis manifesting as acute or chronic infections with high... -
Source data for the publication "A Far-Red Fluorescent Probe to Visualize...
Gram-positive bacteria, in particular Staphylococcus aureus (S. aureus), are the leading bacterial cause of death in high-income countries and can cause invasive infections at... -
High-throughput screening of BAM inhibitors in native membrane environment
The outer membrane insertase of Gram-negative bacteria, BAM, is a key target for urgently needed novel antibiotics. Functional reconstitutions of BAM have so far been limited to... -
Source data for the publication "Phage Paride can kill dormant,...
This dataset enlists all individual datapoints shown in the publication "Phage Paride can kill dormant, antibiotic-tolerant cells of Pseudomonas aeruginosa by direct lytic... -
Characterization of the proteome of E. coli and P. aeruginosa from...
Published in "Phage Paride can kill dormant, antibiotic-tolerant cells of Pseudomonas aeruginosa by direct lytic replication". The goal of this experiment was to assess changes... -
Genome sequences of Pseudomonas phages isolated from environmental samples
Published in "Phage Paride can kill dormant, antibiotic-tolerant cells of Pseudomonas aeruginosa by direct lytic replication"